We are currently extending our study on the role of the hematopoietic microenvironment in the regulation of adult HSCs to embryonic and pathological (neoplastic and non-neoplastic) situations. We are establishing their stem cell signature by analyzing their transcriptomic and proteomic profiles and studying the role of mutual instructions in the maintenance/induction of their stem cell properties ...
Dynamic interactions between stem cells within the hematopoietic niche: therapeutic applications Principal Investigator: MC Le Bousse-Kerdilès (collaboration with JJ Lataillade) Hematopoiesis needs t ...
2014 - Marjorie Durand, Jean-Marc Collombet, Sophie Frasca, Laurent Begot, Jean-Jacques Lataillade*, Marie-Caroline Le Bousse-Kerdilès* and Xavier Holy*. In vivo hypobaric hypoxia performed during th ...